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Investigación y Desarrollo

Investigación

La Historia de IRAM destaca por su vocación para derrotar el Cáncer. Parte fundamental de este trabajo es la constante investigación médica, trabajo realizado por nuestros profesionales que es constantemente presentado en diferentes congresos, publicado en revistas académicas y enseñado como docentes en diferentes universidades en Chile y el extranjero.

22 diciembre 2021

Limb-sparing management with surgical resection, external-beam and intraoperative electron-beam radiation therapy boost for patients with primary soft tissue sarcoma of the extremity

A joint analysis of data from three contributing centres within the intraoperative electron-beam radiation therapy (IOERT) Spanish program was performed to investigate the main contributions of IORT to the multidisciplinary treatment of high-risk extremity soft tissue sarcoma (STS).
22 diciembre 2021

Research opportunities in intraoperative radiation therapy: the next decade 2013–2023

The reality of intraoperative radiation therapy (IORT) practice is consistent with an efficient and highly precise radiation therapy technique to safely boost areas at risk for local recurrence. Long-term clinical experience has shown that IORT-containing multi-modality regimens appear to improve local disease control, if not survival in many diseases.
22 diciembre 2021

Outcome and toxicity using helical tomotherapy for craniospinal irradiation in pediatric medulloblastoma

The objective of this study is to evaluate the tolerability and outcome of craniospinal irradiation (CSI) with helical tomotherapy (HT) in the treatment of medulloblastoma.
22 diciembre 2021

Prognostic Impact of External Beam Radiation Therapy in Patients Treated With and Without Extended Surgery and Intraoperative Electrons for Locally Recurrent Rectal Cancer: 16-Year Experience in a Single Institution

To analyze prognostic factors associated with survival in patients after intraoperative electrons containing resective surgical rescue of locally recurrent rectal cancer (LRRC).
22 diciembre 2021

Preoperative chemoradiation with or without induction oxaliplatin plus 5-fluorouracil in locally advanced rectal cancer

It has been previously reported that a short FOLFOX-4 induction significantly improves pathologic complete response in locally advanced rectal cancer (LARC) patients treated with preoperative chemoradiation (CRT). In a larger and updated patient series, we analyzed FOLFOX-4 efficacy in terms of sphincter preservation and long-term outcomes.
22 diciembre 2021

Programa de screening y tratamiento de cáncer de mama / Screening and treatment program of breast cancer

En enero de 1988 comenzamos un programa piloto de screening en cáncer de mama para mujeres asintomáticas. Una mamografía con dos proyecciones se planificó cada 2 años para las mujeres entre 40 y 50 años y anualmente para aquéllas con 50 años o más.
22 diciembre 2021

Intraoperative electron beam radiotherapy and extended surgical resection for gynecological pelvic recurrent malignancies with and without external beam radiation therapy: Long-term outcomes

To analyze prognostic factors in patients treated with intraoperative electrons containing resective surgical rescue of locally recurrent gynecological cancer (LRGC).
22 diciembre 2021

Clinical significance of VEGFR-2 and 18F-FDG PET/CT SUVmax pretreatment score in predicting the long-term outcome of patients with locally advanced rectal cancer treated with neoadjuvant therapy

Vascular endothelial growth factor receptor-2 (VEGFR-2), epidermal growth factor receptor-1 (EGFR), and cyclooxygenase-2 (COX-2) stimulate key processes involved in tumor progression and are important targets for cancer drugs. 18F-FDG maximum standardized uptake value (SUVmax) is a marker of tumor metabolic activity. The purpose of this study was to measure SUVmax combined with VEGFR-2, EGFR and COX-2 proteins in pretreatment tumor biopsies from patients with locally advanced rectal cancer receiving intensive neoadjuvant treatment and to correlate the findings with clinical outcome.
22 diciembre 2021

Intraoperative radiation therapy opportunities for clinical practice normalization: Data recording and innovative development

Intraoperative radiotherapy (IORT) refers to the delivery of a high dose of radiation at the time of surgery.
22 diciembre 2021

Limb-sparing management with surgical resection, external-beam and intraoperative electron-beam radiation therapy boost for patients with primary soft tissue sarcoma of the extremity

A joint analysis of data from three contributing centres within the intraoperative electron-beam radiation therapy (IOERT) Spanish program was performed to investigate the main contributions of IORT to the multidisciplinary treatment of high-risk extremity soft tissue sarcoma (STS).
22 diciembre 2021

Intraoperative radiotherapy with electrons: fundamentals, results, and innovation

To analyse the programme activity and clinical innovation and/or technology developed over a period of 17 years with regard to the introduction and the use of intraoperative radiotherapy (IORT) as a therapeutic component in a medical–surgical multidisciplinary cancer hospital.

Más de 40 años haciendo compromiso con la vida

Trabajamos día a día por la calidad y la optimización del ambiente de trabajo para lograr la excelencia en el servicio al paciente: nuestro objetivo.

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